Anti-ulcer: Yashtimadhu is beneficial in treating acid peptic disease. Scientific studies have shown that its extract reduces gastric acid secretion and inhibits the formation of peptic ulcers. Yashtimadhu treats ulcers by accelerating mucin excretion by increasing the synthesis of glycoprotein at the gastric mucosa, prolonging the life of the epithelial cells and antipepsin activity. It is also beneficial in the management of aphthous ulcers or mouth sores.

Anti-arthritic: Yashtimadhu has been used in traditional systems of medicine to treat rheumatism and arthritis because of its anti-inflammatory activity.

Anti-allergic: The anti-allergic properties of Yashtimadhu have been attributed to the corticosteroid-like activity of glycyrrhizin and glycyrrhetic acid, also known as enoxolone. The root of Yashtimadhu or Glycyrrhiza glabra Linn. is used as a drug for strengthening muscle and bone, increasing physical strength and treating peptic ulcers. Scientific studies have shown that glycosoids help treat gastric, duodenal and esophageal ulceration or inflammation, heartburn and mouth ulcers.